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February 28 2015

Archimedes
20:44
What a piece of work is ARHGAP11B, how noble in reason, how infinite in faculty!

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
by Wieland B. Huttner, Marta Florio, Mareike Albert, et al.
Science DOI: 10.1126/science.aaa1975
Published Online February 26 2015


Evolutionary expansion of the human neocortex reflects increased amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Here, we analyze the transcriptomes of distinct progenitor subpopulations isolated by a cell polarity-based approach from developing mouse and human neocortex. We identify 56 genes preferentially expressed in human apical and basal radial glia that lack mouse orthologs. Among these, ARHGAP11B has the highest degree of radial glia-specific expression. ARHGAP11B arose from partial duplication of the Rho GTPase-activating-protein–encoding ARHGAP11A on the human lineage after separation from the chimpanzee lineage. Expression of ARHGAP11B in embryonic mouse neocortex promotes basal progenitor generation and self-renewal, and can increase cortical plate area and induce gyrification. Hence, ARHGAP11B may have contributed to evolutionary expansion of human neocortex.
Tags: science
Reposted bysciencepsyentist02mydafsoup-01
Archimedes
02:29
The smallest life-form on Earth
This cryo-electron tomography image reveals the internal structure of an ultra-small bacteria cell like never before. The cell has a very dense interior compartment and a complex cell wall. The darker spots at each end of the cell are most likely ribosomes. The image was obtained from a 3-D reconstruction. The scale bar is 100 nanometers.

Diverse uncultivated ultra-small bacterial cells in groundwater

by Luis R. Comolli, Jillian F. Banfield et al.
Nature Communications 6, No. 6372, 27 February 2015
doi:10.1038/ncomms7372
Tags: science
Reposted byscienceambassadorofdumbscyphiKryptoniteSpecies5618anabeeYggrynothingiseverythingincontrovertiblerecognition

February 27 2015

Archimedes
14:35
Pre-print of Dr. Avijit Roy’s final article for Free Inquiry, to be published in the upcoming April/May issue:
***  “The Virus of Faith” [free PDF-download]  *** 

The Virus of Faith 
by Avijit Roy (1972 - 26 Feb 2015)

Religion, a medieval form of unreason, when combined with modern weaponry becomes a real threat to our freedoms.
—Salman Rushdie

On January 7, 2015, the world witnessed a tragic atrocity committed by soldiers of the so-called religion of peace when two masked Islamists armed with assault rifles entered the offices of Charlie Hebdo (a French satirical weekly newspaper) and killed twelve people, including two police officers, three cartoonists, and seven journalists. The gunmen were heard shouting “Allahu Akbar” (“God is great” in Arabic) and “We have avenged the Prophet Muhammad.” A mere three weeks before, on December 16, 2014, nine gunmen affiliated with the Pakistani Taliban conducted a terrorist attack in Peshawar, Pakistan. They entered a school, opened fire, and killed 145 people, 132 of whom were schoolchildren.

To me, such religious extremism is like a highly contagious virus. My own recent experiences in this regard verify the horrific reality that such religious extremism is a “virus of faith.”

It all started with a book. A national book fair (popularly known as the Ekushey Book Fair) is held every February in Bangladesh. Newly published books are displayed in more than five hundred stalls. Literally thousands of people come to the fair every day and enjoy buying new books. Publishers start preparing for this event quite early as they try to get their books ready for the frenzy of the fair. One of my recent publishers, Jagriti Prakashani, timed the publication of my book Biswasher Virus (Bengali for "The Virus of Faith") to coincide with the book fair of 2014.

As soon as the book was released, it rose to the top of the fair’s bestseller list. At the same time, it hit the cranial nerve of Islamic fundamentalists. The death threats started flowing to my e-mail inbox on a regular basis. I suddenly found myself a target of militant Islamists and terrorists. A well-known extremist by the name of Farabi Shafiur Rahman openly issued death threats to me through his numerous Facebook statuses. In one widely circulated status, Rahman wrote, “Avijit Roy lives in America and so, it is not possible to kill him right now. But he will be murdered when he comes back.”

Continue reading: full-text PDF-download

Dr. Avijit Roy was a Bangladeshi-American blogger, published author, and prominent defender of the freethought movement in Bangladesh. He was well-known for his writings on his self-founded site, Mukto-Mona — an Internet congregation of freethinkers, rationalists, skeptics, atheists, and humanists of mainly Bengali and South Asian descent. As an advocate of atheism, science, and metaphysical naturalism, he published eight Bengali books, and many of his articles have been published in magazines and journals. His last two books, Obisshahser Dorshon (The Philosophy of Disbelief) and Biswasher Virus (The Virus of Faith), have been critically well-received and are popular Bengali books on science, skepticism, and rationalism. At press time, we learned that Dr. Roy was killed and his wife injured by unknown assailants while visiting Bangladesh.
Tags: religion
Reposted byatheism atheism
Archimedes
03:30
Avijit Roy and his wife Rafida Ahmed Banna.
Tags: religion
Reposted byatheism atheism
Archimedes
03:19
Bloggers on hit-list posted by Islamist group in Bangladesh
Tags: religion
Reposted byatheism atheism
Archimedes
03:07
R.I.P. Avijit Roy (murdered 26 February 2015)
Tags: religion
Reposted byatheism atheism
Archimedes
00:36
6605 da25 500
R.I.P. Avijit Roy (murdered 26 February 2015)

Author of the blog "Mukto-mona" encouraging freethinking, humanism, and rationalism in Bangladesh (closed by government):

Mukto-mona (Internet Archive, captured 26 Okt 2014)
Tags: religion
Reposted byatheism atheism

February 26 2015

Archimedes
16:00
The entire LHC is built from a total of 371 standard Lego pieces and each model can be put together in less than ten minutes, even by non-physicists:
http://build-your-own-particle-detector.org
Reposted bysciencejalokim0psyentistdanielbohrercoloredgrayscaletichga
Archimedes
15:30
Ecce homo
Reposted byatheismcliffordkuroinekochrisrobalbesencygenb0ckastridBlue-singdanielbohrerhanspeterwurstsaddamjabolmaxjestemzeroPumpkineerininaTehawanka
Archimedes
15:25
Ecce homo
Reposted byatheismcliffordcygenb0ckastridBlue-singadremdicohanspeterwurstsaddamjestemzeroPumpkineerininaTehawankaRudadredka
Archimedes
13:53
Vortex Lamp
by Carlo Crovato.
Tags: arts untagged
Reposted byyubaba yubaba
Archimedes
11:13
Piggybacking robot feeds you tomatoes while you run.
Tags: untagged
Reposted byRekrut-K Rekrut-K

February 24 2015

Archimedes
09:14
Mystery plume on Mars
Tags: science
Reposted byastronomygrouprunkensteinjalokim0sciencecygenb0ckhanspeterwurstbesenlokrund2015michalkoziolasparagustentacleguyCelebrijaggerrecognitionrunkenstein

February 21 2015

Archimedes
17:16
I'll go vegetarian.
Tags: untagged
Reposted bynewtallicattyGalomtalabesendarthsadicfastjackogharipourwujcioBatthor7oskillzmcflyHypothermiakrolfasoleklolufoaperturenaichluke1coloredgrayscalematussrashfaelkaszebMyBlackWingsfootcrabJaanis93klatkaGantarcoffeeandunicornsTullfrogmontakUbikKurkaWyluzujkrimsonGei0rrelationshitsmoke11IhezalFate46youngandstupidTehawankapowersoupPachadiswingmineurmalborghettofiffeymassivejackPumpkineertrikkniedobrzeOhSnapvongoogenPaseroVirusininasoadystav3bsoavgpLonePoProstuconnlasairoscariotomekwquinne8agiennystettinersiostrafillandiaj0eelcommendanterazielinikrybusmrpafsvvatladykenobirobaltichgaejyopodobnoxszerlitvogelhederetimoorpolaczettoorangeugartespinatlasagnerainbowzombieskilledmyunicornBananikimjongfunsucznikpanpancernydanoniskopankamienmiki77gketlifumask-and-mirrorpsyentistbvdreloveutionTycjaswaczynasasorizanokokompromisekirmelinrzekomywasnaetrivkanikaniIssinsuesssauerrinkaBrutusDanonimowacongrevePsaikoRelentless86Immortalysszponovicheroine88

February 19 2015

Archimedes
21:52
Adriaen van de Venne (1589-1662)
Tags: arts
Reposted byowlswasnaecalamagrostiszycienakrawedzilesatyreszyderakarmazynowatoxicsoulblackandwhitebynlmherzwolekdhoopgreenleafPerpetuummobile

February 14 2015

Archimedes
13:44

OpenPetition:
Büchervernichten in Berlin? Bibliotheken werden kaputt rationalisiert


Bitte wenden Sie sich gegen Pläne des Stiftungsrats der Zentral- und Landesbibliothek Berlin, den Medien-Einkauf künftig über den externen privaten Dienstleister EKZ in Reutlingen abwickeln zu lassen statt wie bisher nur über ausgebildetet LektorInnen der Berliner Bibliotheken.

Bitte wenden Sie sich auch gegen die Pläne, Medien, die länger als zwei Jahre nicht ausgeliehen wurden, zu VERNICHTEN.

Bitte wenden Sie sich gegen weitere Vernichtung von Berliner Bibliothekskultur durch Privatisierung, Rationalisierungen und Einsparungen und setzen Sie sich für eine lebendige Bibliothekskultur (nicht nur) in der Hauptstadt ein.

Unterschriftenliste bei OpenPetition offen bis 13.03.2015:
https://www.openpetition.de/petition/online/buechervernichten-in-berlin-bibliotheken-werden-kaputt-rationalisiert


Intellektuelle Verarmung nach Plan
von Nina Apin, taz vom 14.02.2015

Zuerst waren es nur Gerüchte, seit Montagabend ist es offiziell: Die Zentral-und Landesbibliothek (ZLB), bei den BerlinerInnen für ihr vielfältiges Angebot geschätzt, wird auf Provinzniveau zurückgestutzt. Der Stiftungsrat der Bibliothek beschloss, den Großteil des Medieneinkaufs an einen privaten Bibliotheksdienstleister aus Reutlingen zu delegieren. Der beliefert bereits viele kleinere und mittlere Städte mit "regalfertiger" Medienauswahl. Bestseller, Schulstoff und Populäres - diese Grundausstattung muss nun auch für Berlins Riesenbibliothek mit jährlich 2,4 Millionen ausgeliehener Medien reichen.

Diese Entscheidung, von kritischen Bibliotheksmitarbeitern lange gefürchtet und von der zuständigen Senatsverwaltung für Kultur ebenso lange dementiert, ist ein Skandal: Kompetente Lektoren werden entmachtet, sie dürfen künftig nur noch 6.000 von 30.000 Medien selbst bestellen. Eine Ohrfeige für die Bücherstadt Berlin, für die vielen kleinen Verlage, deren Vielfalt mit 6.000 Titeln nur noch unzureichend abgebildet werden kann. Ein herber Schlag auch für den lokalen Buchhandel, in den nur noch mickrige 20 Prozent des Bibliotheksetats fließen werden. Und vor allem eine himmelschreiende intellektuelle Verarmung: Denn das neue ZLB-Konzept sieht vor, dass Titel, die mehr als zwei Jahre nicht ausgeliehen wurden, vernichtet werden sollen. Richtig gelesen: Vernichtet! Angeblich aus Platzgründen.

Doch das ist Quatsch. In Wirklichkeit geht es dem ZLB-Direktor Volker Heller um den Umbau der Bibliothek. Von der anspruchsvollen Volksbibliothek für alle hin zu einer Zwei-Klassen-Bibliothek: Auf der einen Seite die Masse, die, so will es der Plan, in einem Zentralgebäude bedient werden soll.

Praktischer Spareffekt: Gibt es die "Zentrale", kann man weiter Stadtteilbibliotheken schließen. Merkt ja keiner. Auf der anderen Seite bekommt Berlin einen "Hingucker": die hypermoderne Erlebnis-Bibliothek im Humboldt-Forum. In dieses Schaufenster am Schlossplatz sollen alles Personal und Geld fließen, die man im Massengeschäft zusammenkürzt. Klotzen für die Touristen, während man gleichzeitig dem intellektuellen Fundus dieser Stadt den Boden entzieht. Eine dumme und eine kurzfristige Entscheidung, die einer sich für weltläufig haltenden Metropole unwürdig ist. Aber leider auch symptomatisch ist für die Berliner Kulturpolitik in den letzten Jahren. NINA APIN
Tags: politics
Reposted bywoodynookberlincygenb0cklyderSpinNE555nitroventTokei-IhtodychterFyrstSirenensangpowerToThePoeplemolotovcupcakeylem235ylem23502mydafsoup-01dhoop

February 13 2015

Archimedes
17:24
In spem aeterni consortii

Valentine's Day 2015, Cave of Diros, Peloponnese: Archaeologists have discovered the double burial of a prehistoric couple positioned in an embrace, carbon-dated to 3800 BCE.
Tags: untagged
Reposted bygingergluebesenFreXxXcornis

February 12 2015

Archimedes
19:41
Helena Bonham Carter & Thunnus obesus, 11 Feb 2015.

"By the end of the morning we'd truly bonded. He will be my Valentine."
Tags: arts untagged
Reposted byKohugafohmygodthebritishoopsiakningunacoffeebitchwielorybekkrybusthenatussmentispenetraliaIhezalnotorious-rookiekatastrofoarachnephobicboobiescakecarmenlunaravenheart
Archimedes
17:47

ELSER / engl.:"13 Minutes"

Release Date: 9 April 2015 (Germany)
Director: Oliver Hirschbiegel
Starring: Christian Friedel, Burghart Klaußner, Katharina Schüttler, Johann von Bülow, Peter Becker &c.

Es waren 13 Minuten. 13 Minuten, die gefehlt haben, dass ein Schreiner aus Königsbronn im Alleingang Adolf Hitler tötet. Doch es kam anders an diesem 8. November 1939 im Münchner Bürgerbräukeller: Hitler verlässt den Ort des Attentats zu früh – und Georg Elser wird zum Mann, der die Weltgeschichte hätte ändern und Millionen Menschenleben hätte retten können.

Wer war dieser Mann, der die Gefahr, die von Hitler ausging, früher erkannte als viele andere, der handelte, als alle anderen, einschließlich der deutschen Generäle, mitliefen oder schwiegen? Was sah er, was sie nicht sahen oder sehen wollten? Der Mann der seinen Folterknechten ins Gesicht sagte, dass er das Blutvergießen des absehbaren Weltkrieges verhindern wolle?

(The breath-taking story of a man who nearly would have changed the world. 1939, when Hitler tricked millions of people at the height of his power, one said a radical No: Georg Elser, disparaged as an assassin, is one of the greatest resistance fighters. )
Tags: arts
Reposted bybesen besen
Archimedes
09:16

Measles by the numbers: A race to eradication
The US media are abuzz after an outbreak of measles in Disneyland but the disease will keep on popping up until it is wiped out worldwide.
by Declan Butler
nature, Volume 518, Number 7538, 12 February 2015


Measles A race to eradication
Infographic Download (PDF, 0.4 MB)
Tags: science
Reposted byscience science
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